We tested oligonucleotides capable of forming G-quadruplexes derived from the promotor regions of the c-MYC (Pu19_A2A11) (48), BCL2 and c-KIT oncogenes, as well as the human telomeric repeat sequence (hTel) and TERRA (49) and a G4C2 repeat expansion sequence (50) associated with amyotrophic lateral sclerosis (ALS). Here, BCL2 is linked to amyotrophic lateral sclerosis.