Another study showed that clinical adrenocortical carcinoma (ACC) patients with high METTL1 expression had lower levels of CD8+ T‐cell infiltration and higher levels of macrophage infiltration compared with those with low expression, suggesting that METTL1 exerts a profound effect on tumour immunity in ACC131 (Figure 3). Here, METTL1 is linked to adrenal cortex carcinoma.