At the same time, another meta-analysis of randomized clinical trials aimed to determine the effect of statins on serum levels of TNF-α, MCP-1, VCAM1 and IL-6 in patients with cardiovascular diseases showed that statins have a beneficial effect on reducing the serum levels of TNF-α (Abbasifard et al., 2022). The gene discussed is CCL2; the disease is cardiovascular disorder.