We then took the intersection of DEGs and module genes of MEyellow in TCGA-PAAD dataset and obtained 12 key genes (COL11A1, EPYC, MMP11, KCNK10, SERPINE1, FN1, COL10A1, TGM3, ADAM12, KLK4, XIRP1, and KRT5; Figure 2C). This evidence concerns the gene XIRP1 and pancreatic adenocarcinoma.