We observed no staining of β2-microglobulin-deficient 293T cells expressing SCD of HLA-A*11:01, HLA-B*40:06 and HLA-C*18:02 (the most cross-reactive HLA-A, B and C alleles – Figure 8C), confirming that 4D12 does not cross-react with any of the classical MHC class I alleles tested here. The gene discussed is HLA-A; the disease is Schnyder corneal dystrophy.