WME method showed that the risk of HD was associated with serum MIG (β, 0.152; 95% CI, 0.010–0.295; P = 0.037), IP-10 (β, 0.150; 95% CI, 0.010–0.290; P = 0.036), and IL-16 (β, 0.134; 95% CI, 0.009–0.259, P = 0.036) expression level was positively correlated with HD. Here, CXCL10 is linked to Huntington disease.