TNF and Methicillin-Susceptible Staphylococcus Aureus Infection: In an intradermal infection mice model, IL-1β, IL-6, TNF-α, and IFN-γ were produced by the lymph nodes only after MSSA infection; while in a murine model of endophthalmitis, IL-10, IL-15, IL-11, and some chemokines and receptors were significantly strongly upregulated by MRSA (31).