MUC5AC and Hyperkeratosis: The classic histopathology in DM includes a vacuolar interface dermatitis with epidermal atrophy and hyperkeratosis with mucin deposition in the dermis.[8] However, nonspecific dermatopathological findings can also be seen.[24] Given the above, it seems likely that molecular analysis of genetic markers for SAIDs may help identify SAID patients from the DM patient population, particularly in the absence of autoantibodies.