IFNA1 and lymphoma: Serum IgG highest in LSB and DDF subgroups.Lowest IFN response in HSB and PDF subgroups.Increased prevalence of lymphoma in DDF subgroup.Suggestion of differential response to therapy[21]Chronic comorbid conditions and polypharmacy increased in HSB andPDF subgroups including higher prevalence of fibromyalgia in HSB subgroup.[20]Reduced health related-QoL particularly in HSB subgroup.[18]