TGFBR1 and prostate carcinoma: Furthermore, one possible function of PCAT7 is to serve as ceRNA for miR-324-5p, thus prohibiting access of this miRNA to one of its predicted target mRNAs, TGFBR1. Accordingly, high expression of PCAT7 in prostate carcinoma will sponge miR-324-5p and enhance TGFBR1 expression and TGF-β signaling, which can feed back to the gene and enhance its expression in cells that prepare for metastasis (88).