CTBP1 and colorectal carcinoma: Furthermore, the expression of the lncRNA CTBP1 divergent transcript (CTBP1-DT or CTBP1-AS2) was associated with worse overall survival of CRC patients and positively correlated with TGFB1, SMAD2, and SMAD3 in both colon and rectal adenocarcinoma patients (78).