TGFB1 and lung cancer: The TF FOXP3, which is best known for inducing differentiation of regulatory T cells, can also be misexpressed in NSCLC cells, thus inducing the expression of LINC01232 that associates directly with the IGF2BP2 protein; IGF2BP2 is an RNA-binding protein that associated with and stabilized the TGFBR1 mRNA, thus causing an indirect enhancement of pro-oncogenic TGF-β signaling in the lung cancer cells (47).