TGFB1 and neoplasm: In a different biological context of tumor development, TGF-β is a potent inducer of epithelial-mesenchymal transition (EMT), a cell differentiation change that promotes the dissemination of tumor cells away from the primary tumor, and a process that is not strictly associated with epithelial tumor cells (in carcinomas), but is also relevant for a variety of other tumors, including brain and hematopoietic tumors (6).