They boost the Th1 response, encourage DC growth, promote CD8+ T cells counts, and decrease regulatory T‐cells (Tregs) in the cancer environment Increase the release of IL‐10 by induction of polysaccharide A, suppressing the expansion of tumors via declaring cancer cells' histone deacetylases, causing the immune system to become less inflammatory, and engaging in the presentation and processing of antigens. The gene discussed is CD8A; the disease is cancer.