It is suggested that older patients with diabetes on insulin therapy should carry out self‐monitoring of blood glucose primarily while fasting and before meals, to find out their baseline blood glucose levels; for those at risk of nocturnal hypoglycemia, it is suggested to monitor bedtime and nighttime blood glucose levels additionally based on the patient's condition; however, for those whose blood glucose is controlled stably by OGLMs, frequent monitoring is not required. This evidence concerns the gene INS and Hypoglycemia.