The SET::NUP214 fusion (22) can be generated by either the cryptic translocation t(9;9)(q34;q34) or an intra-chromosomal rearrangement such as the deletion del(9)(q34.11q34.13); it is mostly found in patients with AUL and T-ALL (1, 2, 19, 22). This evidence concerns the gene NUP214 and acute lymphoblastic leukemia.