Less frequent partners for NUP214 are the Sequestosome 1 (SQSTM1) gene at 5q35, involved mostly in T-ALLs (27), and the Ras-related C3 botulinum toxin substrate 1 gene (RAC1) at 7p22 in AML (28). The gene discussed is SQSTM1; the disease is acute myeloid leukemia.