This includes its induction in cancer (5, 6) and in rat progenitor cell lines responding to GDNF (glial cell-derived neurotrophic factor), its non-correlation with GluIIα expression regulation (7), and its intriguing interaction with the 3’UTR of the R1-subunit mRNA of the N-methyl-D-aspartate (NMDA) receptor in mouse fetal cortical neurons (8). This evidence concerns the gene GDNF and cancer.