Furthermore, validation from 95 FNMTC cases carrying three risk alleles of related SNPs (rs965513, rs10759944, rs1867277) at the 9q22.33 locus did not find any deleterious missense mutations in the entire coding sequence of FOXE1. Therefore, the aforementioned FOXE1-associated SNPs were not consistently shown to be associated with FNMTC. The gene discussed is FOXE1; the disease is familial papillary or follicular thyroid carcinoma.