KEGG pathway analysis showed that the main pathways of these disease target genes involved serotonergic synapse, cGMP-PKG signaling pathway, adrenaline signaling in cardiomyocytes, calcium signaling pathway, p53 signaling pathway, platinum resistance, apoptosis, non-small cell lung cancer, bladder cancer, thyroid cancer, renal cell carcinoma, pancreatic cancer, and endometrial cancer. Here, TP53 is linked to hereditary clear cell renal cell carcinoma.