KEGG enrichment analysis revealed serotonergic synapses and cGFMP- PKG signaling pathway, adrenaline signaling in cardiomyocytes, calcium signaling pathway, apoptosis, p53 signaling pathway, platinum resistance, non-small cell lung cancer, bladder cancer, renal cell carcinoma, pancreatic cancer, thyroid cancer, intrauterine membrane cancer, and thyroid hormone signaling pathway. Here, PRKG1 is linked to hereditary clear cell renal cell carcinoma.