In this study, we identified seven novel variants in SCA patients, which were as follows: c.574T > C (CWF19L1), c.388G > A (THG1L), c.8305G > C (VPS13D), c.1721 C > G (RUBCN), c.1033 C > T (GRID2), c.2242 C > T (MME), and c.12913G > T (FAT2). This evidence concerns the gene CWF19L1 and autosomal dominant cerebellar ataxia.