We assessed the co-expression of MSLN and MET in surgical specimens of primary lung tumors (LT, n=25) and brain metastases of lung cancer (BM, n=25), and found that both MSLN and MET were expressed at elevated levels in surgical specimens of brain metastases of lung cancer, and showed a close correlation (Fig. 4A-C). Here, MSLN is linked to lung carcinoma.