m6A regulators were significantly different in expression levels between normal controls and LN patients, and we found that ZC3H13 and IGFBP1 were lowly expressed in LN, and CBLL1, YTHDC1, YTHDC2, YTHDF2, and HNRNPA2B1 were highly expressed in LN, which suggests that m6A modification may be closely related to the development of LN. This evidence concerns the gene ZC3H13 and lobular neoplasia.