PRDX2 and mantle cell lymphoma: To elucidate the role of PRDX2 in MCL, we silenced PRDX2 gene in Z138CT cells, by stable transduction with specific shRNAs lentiviral vector, generating a newly Z138PRDX2 knockdown (KD) MCL cell line, with reduced PRDX2 mRNA (Fig. 5A) and protein levels (Fig. 5B and Supplemental Figure S4).