CREBBP and diffuse large B-cell lymphoma: Examining cohorts of FL and EZB/cluster3 DLBCL (the subset of DLBCL enriched for CREBBP and KMT2D mutations, n = 478 and 319, respectively)4–6,9,17,22–26, we confirmed significant co-occurrence of these two mutations (p values are 1.68E−6 and 1.77E−18, respectively, Supplementary Fig. 1a).