The leucine-rich repeat kinase 2 (LRRK2) is a large multi-domain protein that belongs to the family of tyrosine kinases-like (TKL) protein kinases1, and mutations of the LRRK2 gene have been identified as one of the genetic causes of Parkinson’s disease (PD), the second most common progressive neurodegenerative disorder2,3. This evidence concerns the gene TXK and Parkinson disease.