HSPA8 and amyotrophic lateral sclerosis: A significant reduction in dendritic mRNAs also occurred in motor neurons expressing ALS variants, from a mean count of 160 Hspa8 mRNA spots in control to 60 mRNAs in neurons expressing SOD1G93A, 70 mRNAs in neurons expressing TDP-43G348C, and 50 mRNAs in neurons expressing FUSR521G (Figure 3(c)).