GFAP and Alzheimer disease: To unequivocally determine whether MAO-B expression is increased in reactive astrocytes around dense-core plaques, we performed double fluorescent immunohistochemistry for MAO-B and GFAP with ThioS counterstaining in temporal cortex sections from n = 10 AD (high ADNC) and n = 10 CTRL (not AD/low ADNC) donors.