FGF4 and chondrosarcoma: To investigate whether FGF4, FGF8, and FGF9 induce differential signaling via FGFR1c (referred to as FGFR1 here), we used rat chondrosarcoma (RCS) chondrocytes, an immortal chondrocyte cell line used to model proliferating chondrocytes in the developing limb (Fafilek et al., 2018).