Building on the concept of purine auxotrophy, another study, titled “Yeast-Based High-Throughput Screen Identifies Plasmodium falciparum Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites,” explores the potential of nucleoside transporters as a drug Plasmodium falciparum target (5). Here, SLC29A1 is linked to malaria.