NLRP3 and cardiovascular disorder: It is worth noting in this regard that many natural compounds, such as resveratrol, possess some of the pharmacological properties of gliflozins, including potent inhibition of the NLRP3 inflammasome (Cocetta et al., 2021) and, therefore, may become a useful adjuvant treatment of cardiovascular disease (Sung and Dyck, 2015; Bonnefont-Rousselot, 2016; Raj et al., 2021) and other disorders (Cocetta et al., 2021; Amini et al., 2023).