INS and Glucose intolerance: ↓ glucose intolerance (↓GTT AUC about 12%)↑ insulin sensitivity (↓ITT AUC about 10%)↓ fed glycemia (500 vs. 280mg/dL)↓ fasted glycemia (490 vs. 200mg/dL)↑ glycogen in muscle↓ ectopic fat in muscle↓ triglycerides and free fatty acid