This was also described in a subcutaneous MCA1956 tumor model in mice, where TGF-β signaling in the tumor microenvironment resulted in the plasticity of CD49a−CD49b+Eomes+ NK cells into a CD49a+CD49b+Eomes+ intermediate type 1 ILC1 population and then CD49a+CD49b−Eomesint ILC1s [71]. Here, EOMES is linked to neoplasm.