IL-27 gene polymorphisms (rs153109, rs34833, rs26528, rs17855750, rs181206, and rs40837) were not related to T1D risk in Brazil, and IL-27 genetic mutation did not correlate with gender, age at diagnosis of diabetes, and patients with pancreatic and extrapancreatic autoantibodies (170) (Table 2). This evidence concerns the gene IL27 and diabetes mellitus.