By contrast, another two studies discussed expression of IL-27 from a Northern Chinese Han population, non-obese diabetic (NOD) mice, showing that levels of IL-27, IL-27rα, and gp130 in serum, plasma, and PBMCs from patients with SS and NOD mice were reduced as compared to those in controls, and were negatively related to expression of IgG (131, 132). This evidence concerns the gene IL27RA and synovial sarcoma.