Similarly, CD45RA on CD39+ resting CD4 regulatory T cell, belonging to T cells, was confirmed to be positively correlated with prostate cancer risk through IVW analysis (OR = 1.0029, 95% CI: 1.0008–1.0050, p = 0.0065), with no significant association in weighted median and MR-Egger. The gene discussed is ENTPD1; the disease is Familial prostate cancer.