TP53 and hepatocellular carcinoma: Many studies reported that KIF2C enhanced hepatocellular cancer through the Ras/MAPK and PI3K/Akt signaling pathways and accelerated the growth of cervical cancer by blocking the stimulation of the p53 signaling pathway and activated mTORC1 pathway and promoting tumor cell motility and invasion (An et al., 2021; Moon et al., 2021; Yang et al., 2022).