demonstrated a novel role of YBX1 in stabilizing the heparin‐binding growth factor (HDGF) mRNA by targeting the m5C‐modified site in bladder cancer.[7a] In consistency with this, we found that the expression of YBX1 was frequently upregulated in human ESCC tissues and was mainly localized in the cytoplasm. This evidence concerns the gene HDGF and esophageal squamous cell carcinoma.