SPP1 and congenital bilateral aplasia of vas deferens from CFTR mutation: Previous studies identified LINC00702‐miR‐181b‐5p axis, miR‐127‐5p and miR‐186 affects SPP1 expression in CAVD or OA [54, 57, 61], to the opposite, we identified that lncRNA NEAT1 and lncRNA XIST were key lncRNAs in the network and hsa‐miR‐580‐3p regulated both LRRC15 and SPP1 expression (Figure 11).