Among the 75 germline non-ref NUMTs (Additional file 1: Fig. S5), the one on the intronic region of TCF12 (chrM:7179–7295-to-chr15:57220850, present in one individual) would be interesting as TCF12 is a known tumor-associated gene (COSMIC databases, [53]). The gene discussed is TCF12; the disease is neoplasm.