TP53 and cancer: The results revealed that Hypo-MS4 activity increased with increasing TP53 mutation in 3 out of 4 cancer types, namely, LUAD (P = 0.81), LIHC (P = 0.069), and BRCA (P < 2.22 \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\times {10}^{-16}$$\end{document}×10-16) (Additional file 1, Fig. S12 E, F).