This correlated with decreased levels of TAM markers promoting tumor growth, such as Igfbp7 and Gng5. Although the heterogeneity of the myeloid compartment shifted to a higher ratio of CL2 Mg-TAMs (Fig. 7F), the activation of functional signatures was observed in the majority of Mg-TAM clusters, Mo and BAMs (Fig. 7G). The gene discussed is IGFBP7; the disease is neoplasm.