Using the Chinese Glioma Genome Atlas (CGGA) data set, we correlated GPNMB expression with the TAM marker CD204 and OPN, the macrophage/monocytic marker CD68 and CD14, the leukocytic marker PTRC/CD45, the immunosuppressive macrophage marker CD163 and microglia specific marker Hexosaminidase Subunit Beta (HEXB), Transmembrane Protein 119 (TMEM119) and purinergic receptor P2Y12 (P2RY12). The gene discussed is P2RY12; the disease is central nervous system cancer.