They are relevant to identify since they can provide valuable insight into the underlying mechanisms of UGT2B17 expression as a prognostic and predictive marker in CLL, and in B-cells and dendritic cells previously recognized to produce UGT2B17 minor antigens responsible for cases of graft-vs-host diseases [26, 27]. This evidence concerns the gene UGT2B17 and B-cell chronic lymphocytic leukemia.