Previous studies of hepatic and prostate cancer cell models focused on the canonical promoter located proximal to the first coding exon 1 of the UGT2B17 gene locus and identified several response elements including FOXA1 and hepatocyte nuclear factor 1 as transcriptional regulators for the hepatic and prostate expression [10–12, 24, 25]. Here, UGT2B17 is linked to Familial prostate cancer.