The genetic landscape of EDMD encompasses genes such as EMD, LMNA, SYNE1, SYNE2, FHL1, TMEM43, SUN1, SUN2, and TTN, encoding emerin, lamin A/C, Nesprin-1, Nesprin-2, FHL1, LUMA, SUN1, SUN2, and Titin, respectively. This evidence concerns the gene SYNE2 and Emery-Dreifuss muscular dystrophy.