As another example, IL1RL1 pQTLs colocalised with IL1RL1, IL18R1 and IL18RAP eQTLs detected in multiple cell types with direct effects on the immune system (e.g. T-cells; Supplementary Table S9); these variants were associated with asthma and allergic reactions in the PheWAS. Here, IL1RL1 is linked to allergic disease.