CHST11 and nonpapillary renal cell carcinoma: We also conducted a detailed investigation using the KM plotter database and confirmed that ccRCC patients with high CHST11 expression exhibited an increase in macrophage infiltration, along with a decrease in the infiltration of mesenchymal stem cells, natural killer (NK) T cells, type 1 T-helper cells, and type 2 T-helper cells, which correlated with poor patient prognosis (Fig. 4A–Q).