Ginsenoside Rh2 (37) the major active constituent in red ginseng Panax ginseng (Araliaceae) showed an antiproliferative effect in MCF-7 breast cancer cells, it induces hypermethylation at a CpG site and reduced expression level of C3orf67-AS1, a novel long noncoding RNA. This evidence concerns the gene CFAP20DC and breast carcinoma.