Another report by Mandal et al. Compound (8) shows the ability to suppress breast cancer stem-like cells (CSCs) by stimulating the activity of caspase 3/7 and increasing the intracellular level of reactive oxygen species (ROS) in UA-treated CSCs, resulting in a reduction in mitochondrial membrane potential (Mandal et al. 2021). This evidence concerns the gene CASP3 and breast cancer.