MALAT1 and epilepsy: We also recapitulate the current understanding of the HCN channels in the nervous system (Biel et al., 2009; Wahl-Schott and Biel, 2009; Benarroch, 2013) and pathologies related to their malfunction including epilepsy, neuropathic pain, and Parkinson’s disease, thereby opening the ways for therapeutic approaches targeting these channels.