Additionally, TEC-specific TRAF6 knockout mice have reduced body weight, inflammatory response in the liver, lungs, and kidneys, and exhibit autoantibodies against the liver, lungs, kidneys, small intestine, and colon, while features of human autoimmune hepatitis (AIH) including increased plasmacytes and liver-reactive T cells are also observed in the livers (249). The gene discussed is TRAF6; the disease is autoimmune hepatitis.