Two genes associated with testosterone in female UK Biobank participants are also associated with infertility risk (P<1.00E-03, Bonferroni adjustment for 50 unique genes): TRIM4 (F-ALL, burden test OR=1.03 (1.01–1.05), P=4.05E-04 across all variants with MAF<0.1%) and CYP3A43 (F-EXCL, burden test OR=1.02 (1.01–1.03), P=4.84E-04 across all variants with MAF<1%). The gene discussed is CYP3A43; the disease is Infertility.