STAG3 and female infertility: The eleven novel testosterone associations include a female testosterone-lowering missense variant in STAG3 (chr7:100204708:C:T, β=−0.284, P=2.31E-08); STAG3 is also associated with primary ovarian insufficiency in women83,84, and induces female infertility through the absence of oocytes in knockout mouse models39.