We additionally observed signatures of balancing selection, which maintains multiple alleles in the population through mechanisms such as heterozygote advantage or time-varying fitness60,61, at the female infertility loci GREB1 (StdB2 in the 98.6th-99.4th %ile of SNPs within 10kb of a GWAS Catalog variant) and INHBB (98.5th %ile), and the male infertility locus PCDH15 (98.7th %ile); however, variants at these loci with high probability of association with infertility did not have high balancing selection scores (Supp. The gene discussed is INHBB; the disease is female infertility.