METTL14 and atherosclerosis: For example, in atherosclerosis, myeloid differentiation factor 88 (My88) expression is induced by LPS METTL14 upregulates the My88 phosphorylation level and exacerbates vascular endothelial inflammation, suggesting that METTL14-related m6A is involved in atherosclerotic inflammation (Zheng et al., 2022).