Such as, it has been shown that SNP rs34269950 in the RRACH genome, located in the 3′UTR of RUNX1T1, is significantly regulated by FTO in rural populations in the Caucasus region of Australia, providing important clinical evidence for the association of m6A with metabolic syndrome (Zhou et al., 2021b). This evidence concerns the gene RUNX1T1 and metabolic syndrome.