Meanwhile, human genetic studies on tinnitus that have been replicated in an independent cohort also revealed that genes, such as AF131215.5, BLK, C8orf12, COL11A1, GRK6, MSRA, MFHAS1, XKR6, ANK2, AKAP9, and TSC2, could act as major predictors of the development of tinnitus [11, 20, 21]. This evidence concerns the gene XKR6 and Tinnitus.