Endothelial inflammation plays a pivotal role in the progression of atherosclerosis and CVD (Haybar et al., 2019) leading to the production of proinflammatory mediators such as interleukin (IL)-8, chemokines, monocyte chemoattractant protein-1 (MCP-1), intercellular adhesion molecule-1 (ICAM-1), P-selectin, E-selectin, vascular adhesion molecule-1 (VCAM-1), and other inflammatory factors that attract monocyte and neutrophils which penetrate the arterial wall initiating the inflammatory process of atherogenesis (Chistiakov et al., 2018). This evidence concerns the gene VCAM1 and atherosclerosis.