TLR4 and glaucoma: Reduced expression of genes involved in the pathogenesis of glaucoma was also observed, including chemokines and cytokines (GFAP, Caspase-8, TNFα, IL-1β, IL-6, IL-18, MIP-1α, MIP-1β, MIP-2, MCPI, and IP10), components of the complement cascade (C3, C1Q), Toll-like receptor pathway (TLR4).